Preventing Ovarian Cancer Through Early Excision of Tubes and Late Ovarian Removal
PROTECTOR is an observational research study for women who are at an increased risk of developing ovarian cancer. Some women may carry a fault/alteration in their BRCA1 or BRCA2 gene making them high risk. Whilst, others may be at an increased risk due to a strong family history of cancer or a fault in another ovarian cancer causing gene like RAD51C, RAD51D or BRIP1. This study aims to assess the impact on women of a new two-step option to prevent ovarian cancer. This involves initially just having your tubes (fallopian tubes) removed to prevent ovarian cancer. This is followed by removing your ovaries in a separate operation at a later date of your choosing. The study assesses women’s views and the impact of this approach to prevent ovarian cancer on sexual function, hormone levels, quality of life and overall satisfaction. Outcomes from this new approach are compared to the traditional approach of removal of both tubes and ovaries at the same operation. We also compared this to the well-being of women who do not have an operation.
ChemoINTEL Assay Algorithm: Development Study Synopsis: Advanced Stage Epithelial Ovarian Cancer
A company called Pierian Biosciences Limited aims to develop a method called a prediction algorithm that uses the results from a test on tumour tissue which will give an accurate prediction of the cancer's sensitivity to chemotherapy treatment, or in other words which chemotherapy would be most effective at treating the cancer. This study is aimed toward those with suspected or confirmed ovarian cancer.
If you are interested in taking part in the study or would like more information, please call 0151 702 4496 or email research@lwh.nhs.uk.
ENDO-CARE: Can Supported Weight Loss Reduce Womb Cancer Surgery Complications?
This study is trying to see if for people carrying excess weight, losing even a few pounds reduces complications from surgery for womb cancer and help people recover faster. This involves being chosen at random to either receive standard care or supported weight loss, where a specialist will provide nutritious soups and shakes to assist with weight loss and provide support over the phone.
If you are interested in taking part or would like to learn more about the study, please call 0151 702 4496 or contact the research team at research@lwh.nhs.uk.